Metabolic and immune activation effects of treatment interruption in chronic HIV-1 infection: implications for cardiovascular risk.

Metabolic and immune activation effects of treatment interruption in chronic HIV-1 infection: implications for cardiovascular risk.

Concern about costs and antiretroviral therapy (ART)-associated toxicities led to the consideration of CD4 driven strategies for the management of HIV. That approach was evaluated in the SMART trial that reported an unexpected increase of cardiovascular events after treatment interruption (TI). Our...

Full description

Bibliographic Details
Main Authors: Pablo Tebas, William Keith Henry, Roy Matining, Deborah Weng-Cherng, John Schmitz, Hernan Valdez, Nasreen Jahed, Laurie Myers, William G Powderly, David Katzenstein
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-04-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2292263?pdf=render

Internet

http://europepmc.org/articles/PMC2292263?pdf=render

Similar Items