Increased inflammation is associated with islet autoimmunity and type 1 diabetes in the Diabetes Autoimmunity Study in the Young (DAISY).

Type 1 diabetes (TID) is characterized by a loss of pancreatic islet beta cell function resulting in loss of insulin production. Genetic and environmental factors may trigger immune responses targeting beta cells thus generating islet antibodies (IA). Immune response pathways involve a cascade of ev...

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Bibliographic Details
Main Authors: Kathleen Waugh, Janet Snell-Bergeon, Aaron Michels, Fran Dong, Andrea K Steck, Brigitte I Frohnert, Jill M Norris, Marian Rewers
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5381877?pdf=render