Antidiabetic effect of Chrysophyllum albidum is mediated by enzyme inhibition and enhancement of glucose uptake via 3T3-L1 adipocytes and C2C12 myotubes

Antidiabetic effect of Chrysophyllum albidum is mediated by enzyme inhibition and enhancement of glucose uptake via 3T3-L1 adipocytes and C2C12 myotubes

Objective: To investigate the in vivo and in vitro antidiabetic potential of Chrysophyllum albidum. Methods: The effects of oral treatment with hydro-ethanolic extract (125, 250 and 500 mg/kg) of the stem bark of Chrysophyllum albidum and glibenclamide for 21 d on glucose level, serum enzyme markers...

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Bibliographic Details
Main Authors: Benjamin Kingsley Harley, Rita Akosua Dickson, Isaac Kingsley Amponsah, Robert A Ngala, Dorice Berkoh, Theophilus Christian Fleischer
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:Asian Pacific Journal of Tropical Biomedicine
Subjects:
antidiabetic; c2c12 myotubes; α-glucosidase inhibition; α-amylase inhibition; glucose uptake; chrysophyllum albidum
Online Access:http://www.apjtb.org/article.asp?issn=2221-1691;year=2020;volume=10;issue=9;spage=387;epage=396;aulast=Harley

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http://www.apjtb.org/article.asp?issn=2221-1691;year=2020;volume=10;issue=9;spage=387;epage=396;aulast=Harley

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