Two-Step Reactivation of Dormant Cones in Retinitis Pigmentosa

Two-Step Reactivation of Dormant Cones in Retinitis Pigmentosa

Most retinitis pigmentosa (RP) mutations arise in rod photoreceptor genes, leading to diminished peripheral and nighttime vision. Using a pig model of autosomal-dominant RP, we show glucose becomes sequestered in the retinal pigment epithelium (RPE) and, thus, is not transported to photoreceptors. T...

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Bibliographic Details
Main Authors: Wei Wang, Sang Joon Lee, Patrick A. Scott, Xiaoqin Lu, Douglas Emery, Yongqin Liu, Toshihiko Ezashi, Michael R. Roberts, Jason W. Ross, Henry J. Kaplan, Douglas C. Dean
Format: Article
Language:English
Published: Elsevier 2016-04-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124716302637

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http://www.sciencedirect.com/science/article/pii/S2211124716302637

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