Effects of rifampicin and ketoconazole on the pharmacokinetics of a single oral dose of diethylcarbamazine in healthy volunteers
Diethylcarbamazine (DEC) is the first-line drug for the control and treatment of lymphatic filariasis caused by the Wuchereria bancrofti and Brugia malayi parasite. DEC is rapidly and extensively metabolised in the liver. Rifampicin and ketoconazole are a potent inducer and inhibitor of hepatic cyto...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Prince of Songkla University
2006-12-01
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| Series: | Journal of Health Science and Medical Research (JHSMR) |
| Subjects: | |
| Online Access: | https://www.jhsmr.org/index.php/jhsmr/article/view/616 |