Effects of secretome derived from macrophages exposed to calcium oxalate crystals on renal fibroblast activation

Effects of secretome derived from macrophages exposed to calcium oxalate crystals on renal fibroblast activation

Yoodee et al use label-free quantitative proteomics (nanoLC-ESI-LTQ-Orbitrap MS/MS) to identify 23 significantly altered secreted proteins from calcium oxalate monohydrate (COM)-exposed macrophages secretome. They demonstrate that proteins secreted from macrophages exposed to COM crystals induce ren...

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Bibliographic Details
Main Authors: Sunisa Yoodee, Chadanat Noonin, Kanyarat Sueksakit, Rattiyaporn Kanlaya, Sakdithep Chaiyarit, Paleerath Peerapen, Visith Thongboonkerd
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-02479-2

Internet

https://doi.org/10.1038/s42003-021-02479-2

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