Genetically-determined hyperfunction of the S100B/RAGE axis is a risk factor for aspergillosis in stem cell transplant recipients.

Invasive aspergillosis (IA) is a major threat to the successful outcome of hematopoietic stem cell transplantation (HSCT), although individual risk varies considerably. Recent evidence has established a pivotal role for a danger sensing mechanism implicating the S100B/receptor for advanced glycation...

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Bibliographic Details
Main Authors: Cristina Cunha, Gloria Giovannini, Antonio Pierini, Alain S Bell, Guglielmo Sorci, Francesca Riuzzi, Rosario Donato, Fernando Rodrigues, Andrea Velardi, Franco Aversa, Luigina Romani, Agostinho Carvalho
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22114731/?tool=EBI