Formulation of Nanomicelles to Improve the Solubility and the Oral Absorption of Silymarin

Formulation of Nanomicelles to Improve the Solubility and the Oral Absorption of Silymarin

Two novel nanomicellar formulations were developed to improve the poor aqueous solubility and the oral absorption of silymarin. Polymeric nanomicelles made of Soluplus and mixed nanomicelles combining Soluplus with <span style="font-variant: small-caps;">d</span>-&#945;-toc...

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Bibliographic Details
Main Authors: Vieri Piazzini, Mario D’Ambrosio, Cristina Luceri, Lorenzo Cinci, Elisa Landucci, Anna Rita Bilia, Maria Camilla Bergonzi
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Molecules
Subjects:
silymarin
drug delivery
polymeric nanomicelles
mixed nanomicelles
antioxidant activity
PAMPA
Caco-2 cell line
oral bioavailability
Online Access:https://www.mdpi.com/1420-3049/24/9/1688

Internet

https://www.mdpi.com/1420-3049/24/9/1688

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