Long-term live imaging and multiscale analysis identify heterogeneity and core principles of epithelial organoid morphogenesis

Long-term live imaging and multiscale analysis identify heterogeneity and core principles of epithelial organoid morphogenesis

Abstract Background Organoids are morphologically heterogeneous three-dimensional cell culture systems and serve as an ideal model for understanding the principles of collective cell behaviour in mammalian organs during development, homeostasis, regeneration, and pathogenesis. To investigate the und...

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Bibliographic Details
Main Authors: Lotta Hof, Till Moreth, Michael Koch, Tim Liebisch, Marina Kurtz, Julia Tarnick, Susanna M. Lissek, Monique M. A. Verstegen, Luc J. W. van der Laan, Meritxell Huch, Franziska Matthäus, Ernst H. K. Stelzer, Francesco Pampaloni
Format: Article
Language:English
Published: BMC 2021-02-01
Series:BMC Biology
Online Access:https://doi.org/10.1186/s12915-021-00958-w

Internet

https://doi.org/10.1186/s12915-021-00958-w

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