A TNFSF13B functional variant is not involved in systemic sclerosis and giant cell arteritis susceptibility.

A TNFSF13B functional variant is not involved in systemic sclerosis and giant cell arteritis susceptibility.

<h4>Background</h4>The TNFSF13B (TNF superfamily member 13b) gene encodes BAFF, a cytokine with a crucial role in the differentiation and activation of B cells. An insertion-deletion variant (GCTGT→A) of this gene, leading to increased levels of BAFF, has been recently implicated in the...

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Main Authors: David González-Serna, Elio G Carmona, Norberto Ortego-Centeno, Carmen P Simeón, Roser Solans, José Hernández-Rodríguez, Carlos Tolosa, Santos Castañeda, Javier Narváez, Ferran Martinez-Valle, European GCA Consortium, European Scleroderma Group, Torsten Witte, Thomas Neumann, Julia Holle, Lorenzo Beretta, Luigi Boiardi, Giacomo Emmi, Marco A Cimmino, Augusto Vaglio, Ariane L Herrick, Christopher P Denton, Carlo Salvarani, María C Cid, Ann W Morgan, Carmen Fonseca, Miguel A González-Gay, Javier Martín, Ana Márquez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0209343

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https://doi.org/10.1371/journal.pone.0209343

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