Site-selective electrooxidation of methylarenes to aromatic acetals

Benzylic oxygenation of methylarenes is a direct but challenging method for aldehyde synthesis from simple starting materials. Here, the authors show an electrochemical, site-selective method for the oxidation of methyl benzoheterocycles to aromatic acetals without using chemical oxidants or transit...

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Bibliographic Details
Main Authors: Peng Xiong, Huai-Bo Zhao, Xue-Ting Fan, Liang-Hua Jie, Hao Long, Pin Xu, Zhan-Jiang Liu, Zheng-Jian Wu, Jun Cheng, Hai-Chao Xu
Format: Article
Language:English
Published: Nature Publishing Group 2020-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-16519-8