The significance of metalloproteinases and their inhibitors in gastric cancer

A crucial step in tumor development and metastasis is degradation of the extracellular matrix (ECM). Matrix metalloproteinases (MMPs) are enzymes able to degrade type IV collagen. The proteolytic activity of MMPs is regulated by tissue inhibitors of metalloproteinases (TIMPs). It has been shown that...

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Bibliographic Details
Main Authors: Marta Łukaszewicz-Zając, Barbara Mroczko, Maciej Szmitkowski
Format: Article
Language:English
Published: Index Copernicus International S.A. 2009-06-01
Series:Postępy Higieny i Medycyny Doświadczalnej
Subjects:
Online Access:http://journals.indexcopernicus.com/fulltxt.php?ICID=887593