Roles and Targets of Class I and IIa Histone Deacetylases in Cardiac Hypertrophy

Cardiac hypertrophy occurs in association with heart diseases and ultimately results in cardiac dysfunction and heart failure. Histone deacetylases (HDACs) are post-translational modifying enzymes that can deacetylate histones and non-histone proteins. Research with HDAC inhibitors has provided evid...

Full description

Bibliographic Details
Main Authors: Hae Jin Kee, Hyun Kook
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:Journal of Biomedicine and Biotechnology
Online Access:http://dx.doi.org/10.1155/2011/928326