Varicella zoster virus differentially alters morphology and suppresses proinflammatory cytokines in primary human spinal cord and hippocampal astrocytes

Varicella zoster virus differentially alters morphology and suppresses proinflammatory cytokines in primary human spinal cord and hippocampal astrocytes

Abstract Background Varicella zoster virus (VZV) is a ubiquitous alphaherpesvirus that produces varicella and zoster. VZV can infect multiple cell types in the spinal cord and brain, including astrocytes, producing myelopathy and encephalopathy. While studies of VZV-astrocyte interactions are sparse...

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Bibliographic Details
Main Authors: Andrew N. Bubak, Christina N. Como, Anna M. Blackmon, Dallas Jones, Maria A. Nagel
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Journal of Neuroinflammation
Subjects:
Varicella zoster virus
Encephalitis
Myelopathy
Astrocytes
Cytokines
Immune cell migration
Online Access:http://link.springer.com/article/10.1186/s12974-018-1360-9

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http://link.springer.com/article/10.1186/s12974-018-1360-9

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