A novel virulence strategy for Pseudomonas aeruginosa mediated by an autotransporter with arginine-specific aminopeptidase activity.

The opportunistic human pathogen, Pseudomonas aeruginosa, is a major cause of infections in chronic wounds, burns and the lungs of cystic fibrosis patients. The P. aeruginosa genome encodes at least three proteins exhibiting the characteristic three domain structure of autotransporters, but much rem...

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Bibliographic Details
Main Authors: Jeni C A Luckett, Owen Darch, Chase Watters, Manal Abuoun, Victoria Wright, Esteban Paredes-Osses, Jenny Ward, Hana Goto, Stephan Heeb, Stéphanie Pommier, Kendra P Rumbaugh, Miguel Cámara, Kim R Hardie
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22927813/?tool=EBI