Predicting miRNA Targets by Integrating Gene Regulatory Knowledge with Expression Profiles.

MOTIVATION:microRNAs (miRNAs) play crucial roles in post-transcriptional gene regulation of both plants and mammals, and dysfunctions of miRNAs are often associated with tumorigenesis and development through the effects on their target messenger RNAs (mRNAs). Identifying miRNA functions is critical...

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Bibliographic Details
Main Authors: Weijia Zhang, Thuc Duy Le, Lin Liu, Zhi-Hua Zhou, Jiuyong Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4827848?pdf=render