The CYP19 RS4646 polymorphism IS related to the prognosis of stage I-II and operable stage III breast cancer.

The CYP19 RS4646 polymorphism IS related to the prognosis of stage I-II and operable stage III breast cancer.

Aromatase, encoded by the CYP19 gene, catalyzes the final step of the conversion of androgens to estrogens. Given the critical role of CYP19 in estrogen synthesis, the potential influence of CYP19 rs4646 polymorphism on breast cancer survival, deserves further study.Genotyping for CYP19 rs4646 varia...

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Bibliographic Details
Main Authors: Xiying Shao, Yong Guo, Xiaohong Xu, Yabing Zheng, Jiwen Wang, Zhanhong Chen, Jian Huang, Ping Huang, Jufen Cai, Xiaojia Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4368615?pdf=render

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http://europepmc.org/articles/PMC4368615?pdf=render

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