Mobile genetic element SCCmec-encoded psm-mec RNA suppresses translation of agrA and attenuates MRSA virulence.

Mobile genetic element SCCmec-encoded psm-mec RNA suppresses translation of agrA and attenuates MRSA virulence.

Community acquired-methicillin resistant Staphylococcus aureus (CA-MRSA) is a socially problematic pathogen that infects healthy individuals, causing severe disease. CA-MRSA is more virulent than hospital associated-MRSA (HA-MRSA). The underlying mechanism for the high virulence of CA-MRSA is not kn...

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Bibliographic Details
Main Authors: Chikara Kaito, Yuki Saito, Mariko Ikuo, Yosuke Omae, Han Mao, Gentaro Nagano, Tomoko Fujiyuki, Shunsuke Numata, Xiao Han, Kazuaki Obata, Setsuo Hasegawa, Hiroki Yamaguchi, Koiti Inokuchi, Teruyo Ito, Keiichi Hiramatsu, Kazuhisa Sekimizu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3617227?pdf=render

Internet

http://europepmc.org/articles/PMC3617227?pdf=render

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