S100A8/A9 stimulates keratinocyte proliferation in the development of squamous cell carcinoma of the skin via the receptor for advanced glycation-end products.

Squamous cell carcinoma (SCC) is the most common neoplasm in organ transplant recipients (OTR) on long-term immunosuppression and occurs 60- to 100-fold more frequently than in the general population. Here, we present the receptor for advanced glycation end products (RAGE) and S100A8/A9 as important...

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Bibliographic Details
Main Authors: Guergana Iotzova-Weiss, Piotr J Dziunycz, Sandra N Freiberger, Severin Läuchli, Jürg Hafner, Thomas Vogl, Lars E French, Günther F L Hofbauer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4374726?pdf=render