Lactobacillus sakei OK67 ameliorates collagen-induced arthritis in mice by inhibiting NF-κB activation and restoring Th17/Treg cell balance
The anti-inflammatory effects of Th17-inhibiting bacterial strain Lactobacillus sakei OK67 were investigated in DMA/1J mice with collagen II-induced arthritis (CIA). OK67 significantly suppressed IL-6/TGF-β-induced differentiation of splenic T cells into Th17 cells in vitro. Oral administration of O...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2015-10-01
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| Series: | Journal of Functional Foods |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1756464615003904 |