Systemic inhibition of myeloid dendritic cells by circulating HLA class I molecules in HIV-1 infection

<p>Abstract</p> <p>Background</p> <p>HIV-1 infection is associated with profound dysfunction of myeloid dendritic cells, for reasons that remain ill-defined. Soluble HLA class I molecules can have important inhibitory effects on T cells and NK cells, but may also contri...

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Bibliographic Details
Main Authors: Huang Jinghe, Al-Mozaini Maha, Rogich Jerome, Carrington Mary F, Seiss Katherine, Pereyra Florencia, Lichterfeld Mathias, Yu Xu G
Format: Article
Language:English
Published: BMC 2012-01-01
Series:Retrovirology
Subjects:
HLA
Online Access:http://www.retrovirology.com/content/9/1/11