A liquid chromatography-mass spectrometry workflow for in-depth quantitation of fatty acid double bond location isomers

Tracing compositional changes of fatty acids (FAs) is frequently used as a means of monitoring metabolic alterations in perturbed biological states. Given that more than half of FAs in the mammalian lipidome are unsaturated, quantitation of FAs at a carbon-carbon double bond (C=C) location level is...

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Bibliographic Details
Main Authors: Jing Zhao, Mengxuan Fang, Yu Xia
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227521000924