The Effects of Disease Models of Nuclear Actin Polymerization on the Nucleus

The Effects of Disease Models of Nuclear Actin Polymerization on the Nucleus

Actin plays a crucial role in regulating multiple processes within the nucleus, including transcription and chromatin organization. However, the polymerization state of nuclear actin remains controversial, and there is no evidence for persistent actin filaments in a normal interphase nucleus. Furthe...

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Bibliographic Details
Main Authors: Leonid Serebryannyy, Michaela Yuen, Megan Parilla, Sandra T Cooper, Primal de Lanerolle
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-10-01
Series:Frontiers in Physiology
Subjects:
Chromatin
RNA Polymerase II
nuclear structure
Nuclear actin
Intranuclear rod myopathy
nuclear filaments
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2016.00454/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphys.2016.00454/full

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