The differential formation of the LINC-mediated perinuclear actin cap in pluripotent and somatic cells.

The differential formation of the LINC-mediated perinuclear actin cap in pluripotent and somatic cells.

The actin filament cytoskeleton mediates cell motility and adhesion in somatic cells. However, whether the function and organization of the actin network are fundamentally different in pluripotent stem cells is unknown. Here we show that while conventional actin stress fibers at the basal surface of...

Full description

Bibliographic Details
Main Authors: Shyam B Khatau, Sravanti Kusuma, Donny Hanjaya-Putra, Prashant Mali, Linzhao Cheng, Jerry S H Lee, Sharon Gerecht, Denis Wirtz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3344930?pdf=render

Internet

http://europepmc.org/articles/PMC3344930?pdf=render

Similar Items