Optogenetic self-stimulation in the nucleus accumbens: D1 reward versus D2 ambivalence.

The nucleus accumbens (NAc) contains multiple subpopulations of medium spiny neurons (MSNs). One subpopulation expresses D1-type dopamine receptors, another expresses D2-type receptors, and a third expresses both. The relative roles in NAc of D1 neurons versus D2 neurons in appetitive motivation wer...

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Bibliographic Details
Main Authors: Shannon L Cole, Mike J F Robinson, Kent C Berridge
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0207694