Dissecting the critical factors for thermodynamic stability of modular proteins using molecular modeling approach.

Repeat proteins have recently attracted much attention as alternative scaffolds to immunoglobulin antibodies due to their unique structural and biophysical features. In particular, repeat proteins show high stability against temperature and chaotic agents. Despite many studies, structural features f...

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Bibliographic Details
Main Authors: Yuno Lee, Joong-jae Lee, Songmi Kim, Sang-Chul Lee, Jieun Han, Woosung Heu, Keunwan Park, Hyun Jung Kim, Hae-Kap Cheong, Dongsup Kim, Hak-Sung Kim, Keun Woo Lee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4029881?pdf=render