Pancreatic islet macroencapsulation using microwell porous membranes

Abstract Allogeneic islet transplantation into the liver in combination with immune suppressive drug therapy is widely regarded as a potential cure for type 1 diabetes. However, the intrahepatic system is suboptimal as the concentration of drugs and nutrients there is higher compared to pancreas, wh...

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Bibliographic Details
Main Authors: Katarzyna Skrzypek, Milou Groot Nibbelink, Jéré van Lente, Mijke Buitinga, Marten A. Engelse, Eelco J. P. de Koning, Marcel Karperien, Aart van Apeldoorn, Dimitrios Stamatialis
Format: Article
Language:English
Published: Nature Publishing Group 2017-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-09647-7