Acerola exosome-like nanovesicles to systemically deliver nucleic acid medicine via oral administration

Extracellular vesicles derived from mammalian cells could be useful carriers for drug delivery systems (DDSs); however, with regard to clinical application, there are several issues to be overcome. Acerola (Malpighia emarginata DC.) is a popular health food. In this study, the feasibility of orally...

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Bibliographic Details
Main Authors: Tomohiro Umezu, Masakatsu Takanashi, Yoshiki Murakami, Shin-ichiro Ohno, Kohsuke Kanekura, Katsuko Sudo, Kenichi Nagamine, Shin Takeuchi, Takahiro Ochiya, Masahiko Kuroda
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:Molecular Therapy: Methods & Clinical Development
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2329050121000462