Multi-Catalytic Route for the Synthesis of (<i>S</i>)-Tembamide

Multi-Catalytic Route for the Synthesis of (<i>S</i>)-Tembamide

Enantiopure &#946;-amino alcohols constitute one of the most significant building blocks for the synthesis of active pharmaceutical ingredients. Despite the availability of a range of chiral &#946;-amino alcohols from a chiral pool, there is a growing demand for new enantioselective syntheti...

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Bibliographic Details
Main Authors: Laura Leemans, Marc D. Walter, Frank Hollmann, Anett Schallmey, Luuk M. van Langen
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Catalysts
Subjects:
enantioselectivity
chemoenzymatic cascade
hydroxynitrile lyase
lipase
raney ni
hydrocyanation
transesterification
catalytic hydrogenation
nitrile reduction
tembamide
Online Access:https://www.mdpi.com/2073-4344/9/10/822

Internet

https://www.mdpi.com/2073-4344/9/10/822

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