BMP-induced reprogramming of the neural retina into retinal pigment epithelium requires Wnt signalling

BMP-induced reprogramming of the neural retina into retinal pigment epithelium requires Wnt signalling

In vertebrates, the retinal pigment epithelium (RPE) and photoreceptors of the neural retina (NR) comprise a functional unit required for vision. During vertebrate eye development, a conversion of the RPE into NR can be induced by growth factors in vivo at optic cup stages, but the reverse process,...

Full description

Bibliographic Details
Main Authors: Jörg Steinfeld, Ichie Steinfeld, Alexander Bausch, Nicola Coronato, Meggi-Lee Hampel, Heike Depner, Paul G. Layer, Astrid Vogel-Höpker
Format: Article
Language:English
Published: The Company of Biologists 2017-07-01
Series:Biology Open
Subjects:
Cell fate
Progenitors
Retinal pigment epithelium
Regeneration
Retina
Stem cells
Transdifferentiation
Re-specification
Online Access:http://bio.biologists.org/content/6/7/979

Internet

http://bio.biologists.org/content/6/7/979

Similar Items