Human Monocyte-Derived Osteoclasts Are Targeted by Staphylococcal Pore-Forming Toxins and Superantigens.

Staphylococcus aureus is the leading cause of bone and joint infections (BJIs). Staphylococcal pathogenesis involves numerous virulence factors including secreted toxins such as pore-forming toxins (PFTs) and superantigens. The role of these toxins on BJI outcome is largely unknown. In particular, f...

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Bibliographic Details
Main Authors: Sacha Flammier, Jean-Philippe Rasigade, Cédric Badiou, Thomas Henry, François Vandenesch, Frédéric Laurent, Sophie Trouillet-Assant
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4774977?pdf=render