Effects on immune cells of a new 1,8-naphthyridin-2-one derivative and its analogues as selective CB2 agonists: implications in multiple sclerosis.

Effects on immune cells of a new 1,8-naphthyridin-2-one derivative and its analogues as selective CB2 agonists: implications in multiple sclerosis.

The efficacy of cannabinoids in the treatment of multiple sclerosis is widely documented; however their use is limited by psychoactivity mainly ascribed to the activation of the cannabinoid receptor CB1. Emerging findings support as alternative strategy in the treatment of neurodegenerative disorder...

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Bibliographic Details
Main Authors: Anna Maria Malfitano, Chiara Laezza, Alba D'Alessandro, Claudio Procaccini, Giuseppe Saccomanni, Tiziano Tuccinardi, Clementina Manera, Marco Macchia, Giuseppe Matarese, Patrizia Gazzerro, Maurizio Bifulco
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3641032?pdf=render

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http://europepmc.org/articles/PMC3641032?pdf=render

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