Anti-amyloid-β-mediated positron emission tomography imaging in Alzheimer's disease mouse brains.

Antibody-mediated imaging of amyloid β (Aβ) in Alzheimer's disease (AD) offers a promising strategy to detect and monitor specific Aβ species, such as oligomers, that have important pathological and therapeutic relevance. The major current limitation of antibodies as a diagnostic and imaging de...

Full description

Bibliographic Details
Main Authors: Daniel McLean, Michael J Cooke, Yuanfei Wang, David Green, Paul E Fraser, Peter St George-Hyslop, Molly S Shoichet
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3528731?pdf=render