Overview of methodologies for T-cell receptor repertoire analysis

Overview of methodologies for T-cell receptor repertoire analysis

Abstract Background The T-cell receptor (TCR), located on the surface of T cells, is responsible for the recognition of the antigen-major histocompatibility complex, leading to the initiation of an inflammatory response. Analysing the TCR repertoire may help to gain a better understanding of the imm...

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Bibliographic Details
Main Authors: Elisa Rosati, C Marie Dowds, Evaggelia Liaskou, Eva Kristine Klemsdal Henriksen, Tom H Karlsen, Andre Franke
Format: Article
Language:English
Published: BMC 2017-07-01
Series:BMC Biotechnology
Subjects:
T-cell receptor (TCR)
TCR profiling
TCR repertoire
Immune repertoire
Immunogenetics
Immunogenomics
Online Access:http://link.springer.com/article/10.1186/s12896-017-0379-9

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http://link.springer.com/article/10.1186/s12896-017-0379-9

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