Pre- and postovulatory aging of murine oocytes affect the transcript level and poly(A) tail length of maternal effect genes.

Pre- and postovulatory aging of murine oocytes affect the transcript level and poly(A) tail length of maternal effect genes.

Maternal effect genes code for oocyte proteins that are important for early embryogenesis. Transcription in oocytes does not take place from the onset of meiotic progression until zygotic genome activation. During this period, protein levels are regulated posttranscriptionally, for example by poly(A...

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Bibliographic Details
Main Authors: Debora Dankert, Hannah Demond, Tom Trapphoff, Martyna Heiligentag, Katrin Rademacher, Ursula Eichenlaub-Ritter, Bernhard Horsthemke, Ruth Grümmer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4182777?pdf=render

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http://europepmc.org/articles/PMC4182777?pdf=render

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