Synaptic roles for phosphomannomutase type 2 in a new Drosophila congenital disorder of glycosylation disease model

Congenital disorders of glycosylation (CDGs) constitute a rapidly growing family of human diseases resulting from heritable mutations in genes driving the production and modification of glycoproteins. The resulting symptomatic hypoglycosylation causes multisystemic defects that include severe neurol...

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Bibliographic Details
Main Authors: William M. Parkinson, Michelle Dookwah, Mary Lynn Dear, Cheryl L. Gatto, Kazuhiro Aoki, Michael Tiemeyer, Kendal Broadie
Format: Article
Language:English
Published: The Company of Biologists 2016-05-01
Series:Disease Models & Mechanisms
Subjects:
Wnt
Online Access:http://dmm.biologists.org/content/9/5/513