Dexmedetomidine expands monocytic myeloid-derived suppressor cells and promotes tumour metastasis after lung cancer surgery

Dexmedetomidine expands monocytic myeloid-derived suppressor cells and promotes tumour metastasis after lung cancer surgery

Abstract Background Dexmedetomidine (DEX) has been reported to promote tumour metastases. However the underlying mechanisms remain unclear. The purpose of this study was to investigate whether DEX promotes tumour metastasis by inducing myeloid-derived suppressor cells (MDSC) in the context of surger...

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Bibliographic Details
Main Authors: Xiaosan Su, Yaodong Fan, Liu Yang, Jie Huang, Fei Qiao, Yu Fang, Jun Wang
Format: Article
Language:English
Published: BMC 2018-12-01
Series:Journal of Translational Medicine
Subjects:
Dexmedetomidine
Myeloid-derived suppressor cells
Lung cancer
Metastasis
Perioperative care
Online Access:http://link.springer.com/article/10.1186/s12967-018-1727-9

Internet

http://link.springer.com/article/10.1186/s12967-018-1727-9

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