Structural basis for the transformation pathways of the sodium naproxen anhydrate–hydrate system

Structural basis for the transformation pathways of the sodium naproxen anhydrate–hydrate system

Crystal structures are presented for two dihydrate polymorphs (DH-I and DH-II) of the non-steroidal anti-inflammatory drug sodium (S)-naproxen. The structure of DH-I is determined from twinned single crystals obtained by solution crystallization. DH-II is obtained by solid-state routes, and its stru...

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Bibliographic Details
Main Authors: Andrew D. Bond, Claus Cornett, Flemming H. Larsen, Haiyan Qu, Dhara Raijada, Jukka Rantanen
Format: Article
Language:English
Published: International Union of Crystallography 2014-09-01
Series:IUCrJ
Subjects:
pharmaceutical
hydrate
X-ray diffraction
solid-state NMR
DFT-D
Online Access:http://scripts.iucr.org/cgi-bin/paper?S2052252514015450

Internet

http://scripts.iucr.org/cgi-bin/paper?S2052252514015450

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