Patient-derived organoids and high grade serous ovarian cancer: from disease modeling to personalized medicine
Abstract Background High grade serous ovarian cancer (HGSOC) is among the deadliest human cancers and its prognosis remains extremely poor. Tumor heterogeneity and rapid acquisition of resistance to conventional chemotherapeutic approaches strongly contribute to poor outcome of patients. The clinica...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-03-01
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Series: | Journal of Experimental & Clinical Cancer Research |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13046-021-01917-7 |