Novel natural mutations in the hepatitis B virus reverse transcriptase domain associated with hepatocellular carcinoma.

Novel natural mutations in the hepatitis B virus reverse transcriptase domain associated with hepatocellular carcinoma.

Hepatitis B Virus (HBV) mutations play a role in the development of hepatocellular carcinoma (HCC). However, the association between HBV polymerase gene mutations and HCC has not been reported. In this study, we conducted a multi-stage study to identify HCC-related mutations in the reverse transcrip...

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Bibliographic Details
Main Authors: Yan Wu, Yu Gan, Fumin Gao, Zhimei Zhao, Yan Jin, Yu Zhu, Zhihan Sun, Hao Wu, Taoyang Chen, Jinbing Wang, Yan Sun, Chunsun Fan, Yongbing Xiang, Gengsun Qian, John D Groopman, Jianren Gu, Hong Tu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4006920?pdf=render

Internet

http://europepmc.org/articles/PMC4006920?pdf=render

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