Parallel evolution of influenza across multiple spatiotemporal scales

Parallel evolution of influenza across multiple spatiotemporal scales

Viral variants that arise in the global influenza population begin as de novo mutations in single infected hosts, but the evolutionary dynamics that transform within-host variation to global genetic diversity are poorly understood. Here, we demonstrate that influenza evolution within infected humans...

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Bibliographic Details
Main Authors: Katherine S Xue, Terry Stevens-Ayers, Angela P Campbell, Janet A Englund, Steven A Pergam, Michael Boeckh, Jesse D Bloom
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-06-01
Series:eLife
Subjects:
clonal interference
influenza
epidemiology
deep sequencing
antigenic evolution
hemagglutinin
Online Access:https://elifesciences.org/articles/26875

Internet

https://elifesciences.org/articles/26875

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