Liquid biopsy with droplet digital PCR targeted to specific mutations in plasma cell-free tumor DNA can detect ovarian cancer recurrence earlier than CA125

Liquid biopsy with droplet digital PCR targeted to specific mutations in plasma cell-free tumor DNA can detect ovarian cancer recurrence earlier than CA125

Objective: Ovarian cancer (OC) is an intractable gynecological tumor, and frequent recurrence is experienced within a few years even after the complete eradication of tumor tissues by radical resection and neo-adjuvant chemotherapies. The conventional recurrence marker, CA125, is widely used for fol...

Full description

Bibliographic Details
Main Authors: Takamichi Minato, Shin Ito, Bin Li, Haruna Fujimori, Mai Mochizuki, Kazunori Yamaguchi, Keiichi Tamai, Muneaki Shimada, Hideki Tokunaga, Shogo Shigeta, Ikuro Sato, Hiroshi Shima, Hidekazu Yamada, Nobuo Yaegashi, Jun Yasuda
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:Gynecologic Oncology Reports
Subjects:
ctDNA
Ovarian cancer
ddPCR
CA125
Online Access:http://www.sciencedirect.com/science/article/pii/S235257892100151X

Internet

http://www.sciencedirect.com/science/article/pii/S235257892100151X

Similar Items