Identification of two independent risk factors for lupus within the MHC in United Kingdom families.

The association of the major histocompatibility complex (MHC) with SLE is well established yet the causal variants arising from this region remain to be identified, largely due to inadequate study design and the strong linkage disequilibrium demonstrated by genes across this locus. The majority of s...

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Bibliographic Details
Main Authors: Michelle M A Fernando, Christine R Stevens, Pardis C Sabeti, Emily C Walsh, Alasdair J M McWhinnie, Anila Shah, Todd Green, John D Rioux, Timothy J Vyse
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-11-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2065882?pdf=render