Homozygous Splice Site Mutation in <i>ZP1</i> Causes Familial Oocyte Maturation Defect

Homozygous Splice Site Mutation in <i>ZP1</i> Causes Familial Oocyte Maturation Defect

In vitro fertilization (IVF) involves controlled ovarian hyperstimulation using hormones to produce large numbers of oocytes. The success of IVF is tightly linked to the availability of mature oocytes. In most cases, about 70% to 80% of the oocytes are mature at the time of retrieval, however, in ra...

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Bibliographic Details
Main Authors: Özlem Okutman, Cem Demirel, Firat Tülek, Veronique Pfister, Umut Büyük, Jean Muller, Nicolas Charlet-Berguerand, Stéphane Viville
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Genes
Subjects:
immature oocytes
oocyte maturation defect
female infertility
Online Access:https://www.mdpi.com/2073-4425/11/4/382

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https://www.mdpi.com/2073-4425/11/4/382

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