Disruption of the Opal Stop Codon Attenuates Chikungunya Virus-Induced Arthritis and Pathology

Disruption of the Opal Stop Codon Attenuates Chikungunya Virus-Induced Arthritis and Pathology

Chikungunya virus (CHIKV) is a mosquito-borne alphavirus responsible for several significant outbreaks of debilitating acute and chronic arthritis and arthralgia over the past decade. These include a recent outbreak in the Caribbean islands and the Americas that caused more than 1 million cases of v...

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Bibliographic Details
Main Authors: Jennifer E. Jones, Kristin M. Long, Alan C. Whitmore, Wes Sanders, Lance R. Thurlow, Julia A. Brown, Clayton R. Morrison, Heather Vincent, Kayla M. Peck, Christian Browning, Nathaniel Moorman, Jean K. Lim, Mark T. Heise, Terence S. Dermody
Format: Article
Language:English
Published: American Society for Microbiology 2017-11-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/8/6/e01456-17

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http://mbio.asm.org/cgi/content/full/8/6/e01456-17

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