Risk Alleles in/near ADCY5, ADRA2A, CDKAL1, CDKN2A/B, GRB10, and TCF7L2 Elevate Plasma Glucose Levels at Birth and in Early Childhood: Results from the FAMILY Study.

BACKGROUND:Metabolic abnormalities that lead to type 2 diabetes mellitus begin in early childhood. OBJECTIVES:We investigate whether common genetic variants identified in adults have an effect on glucose in early life. METHODS:610 newborns, 463 mothers, and 366 fathers were included in the present s...

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Bibliographic Details
Main Authors: Zahra N Sohani, Sonia S Anand, Sebastien Robiou-du-Pont, Katherine M Morrison, Sarah D McDonald, Stephanie A Atkinson, Koon K Teo, David Meyre
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4822946?pdf=render