Formulation, stability testing, and analytical characterization of melatonin-based preparation for clinical trial

A new institutional clinical trial assessed the improvement of sleep disorders in 40 children with autism treated by immediate-release melatonin formulation in different regimens (0.5 mg, 2 mg, and 6 mg daily) for one month. The objectives of present study were to (i) prepare low-dose melatonin hard...

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Bibliographic Details
Main Authors: Samira Filali, Charlotte Bergamelli, Mamadou Lamine Tall, Damien Salmon, Diane Laleye, Carole Dhelens, Elhadji Diouf, Christine Pivot, Fabrice Pirot
Format: Article
Language:English
Published: Elsevier 2017-08-01
Series:Journal of Pharmaceutical Analysis
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2095177917300461