Anterior thalamic nuclei deep brain stimulation inhibits mossy fiber sprouting via 3′,5′-cyclic adenosine monophosphate/protein kinase A signaling pathway in a chronic epileptic monkey model

Abstract. Background. Anterior thalamic nuclei (ATN) deep brain stimulation (DBS) is an effective method of controlling epilepsy, especially temporal lobe epilepsy. Mossy fiber sprouting (MFS) plays an indispensable role in the pathogenesis and progression of epilepsy, but the effect of ATN-DBS on M...

Full description

Bibliographic Details
Main Authors: Ting-Ting Du, Ying-Chuan Chen, Guan-Yu Zhu, De-Feng Liu, Yu-Ye Liu, Tian-Shuo Yuan, Xin Zhang, Jian-Guo Zhang, Ning-Ning Wang.
Format: Article
Language:English
Published: Wolters Kluwer 2021-02-01
Series:Chinese Medical Journal
Online Access:http://journals.lww.com/10.1097/CM9.0000000000001302