HDAC7 is a repressor of myeloid genes whose downregulation is required for transdifferentiation of pre-B cells into macrophages.

HDAC7 is a repressor of myeloid genes whose downregulation is required for transdifferentiation of pre-B cells into macrophages.

B lymphopoiesis is the result of several cell-commitment, lineage-choice, and differentiation processes. Every differentiation step is characterized by the activation of a new, lineage-specific, genetic program and the extinction of the previous one. To date, the central role of specific transcripti...

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Bibliographic Details
Main Authors: Bruna Barneda-Zahonero, Lidia Román-González, Olga Collazo, Haleh Rafati, Abul B M M K Islam, Lars H Bussmann, Alessandro di Tullio, Luisa De Andres, Thomas Graf, Núria López-Bigas, Tokameh Mahmoudi, Maribel Parra
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-05-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3656156?pdf=render

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http://europepmc.org/articles/PMC3656156?pdf=render

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