HDAC7 is a repressor of myeloid genes whose downregulation is required for transdifferentiation of pre-B cells into macrophages.
B lymphopoiesis is the result of several cell-commitment, lineage-choice, and differentiation processes. Every differentiation step is characterized by the activation of a new, lineage-specific, genetic program and the extinction of the previous one. To date, the central role of specific transcripti...
Main Authors: | Bruna Barneda-Zahonero, Lidia Román-González, Olga Collazo, Haleh Rafati, Abul B M M K Islam, Lars H Bussmann, Alessandro di Tullio, Luisa De Andres, Thomas Graf, Núria López-Bigas, Tokameh Mahmoudi, Maribel Parra |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-05-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC3656156?pdf=render |
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